REGISTER HERE to join Society of Toxicology for a live webinar workshop chaired by Dr. L. Cody Smith – Single Cell Applications in Mechanistic Toxicology – on April 2, 2020 at 12:00 – 1:30 pm EDT.

Tap images below for video presentations

Chemical Threats
Presenter Lab Presentation Title
J. Andres D. Laskin The Use of Molecular Imaging Methodology to Develop a Feed-Forward Model to Assess Lung Function in Mustard-Induced Lung Injury
Y. Chang Gerecke Inhibition of Matrix Metalloproteinase 9 (MMP9) Suppresses Inflammation and Enhances Wound Healing in Mouse Skin
M. Gordon Gordon Epithelial Repair in the Rabbit Cornea following Exposure to Sulfur Mustard
Y. Jan J. Laskin Nitrogen Mustard Induces Mitochondria-Mediated Apoptosis Associated with Endoplasmic Reticulum Stress-Regulated MAPK Signaling in Human HaCaT Keratinocytes
L. Joseph J. Laskin Rabbit Conjunctiva as a Target for Ocular Injury Induced by Sulfur Mustard
H. Kim Heck Characterization of Molecular Pattern in Sensory Pain Signaling and Its Neurotransmitters on Mouse Skin following Mustard Exposure
R. Malaviya D. Laskin Pulmonary Effects of Inhaled Sulfur Mustard in Rats
A. Murray D. Laskin Farnesoid X Receptor Regulates Macrophage Activation in Nitrogen Mustard-Induced Lung Injury in a Sex-Dependent Manner
R. Rancourt D. Laskin Microparticle Detection and Phospatidlyserine Exposure in Airway Surface Liquid in Response to Nitrogen Mustard
T. Roldan Sinko Optimizing Nitrogen Mustard Administration to Obtain Reproducible Model Vesicant Skin Burns
V. Sunil D. Laskin Differential Activation of Alveolar Type II Epithelial Cells and Alveolar Macrophages after Nitrogen Mustard Exposure
S. Yang J. Laskin Nitrogen Mustard Targets Pathways for Tetrahydrobiopterin Biosynthesis in Human Keratinocytes
Presenter Lab Presentation Title
Y. An J. Laskin Potential Role of Ferroptosis in Toxicity Induced by 9,10-Phenanthrenequinone in Human Lung Epithelia Calu-1 Cells
T. Banota D. Laskin The Development of Pulmonary Inflammation and Injury in a Mouse Model of Non-Alcoholic Steatohepatitis
J. Carnino Jin Effects of Ozone-Generated Microvesicles and MV-MiR-199a-3p on Inflammatory Lung Responses in Alveolar Macrophages
E. Chung Panettieri Glucocorticoids Rescue TFG-β1-Mediated β2- Adrenergic Receptor Dysfunction by Attenuating Gene Expression
C. Gardner D. Laskin Depletion of CD11b+ Alveolar Macrophages Exacerbates Lung Injury and Oxidative Stress following Ozone Inhalation
A. Gow Gow Lung Function: It’s Not Just Breathing
M. Han D. Laskin Involvement of Galectin-3 in Maintaining Barrier Integrity of Lung Vasculature
D. Laskin D. Laskin Macrophage Phenotype and Inflammation in Lung Injury and Resolution: Role of Lipid Metabolism
J. Lee D. Laskin Valproic Acid Blunts Lung Injury, Oxidative Stress, Inflammation, and Altered Pulmonary Mechanics Induced by Inhaled Ozone
C. Malcolm D. Laskin PPARγ Regulates the Inflammatory Response to Ozone-Induced Lung Injury in Mice
A. Murray D. Laskin Combination of Functional Testing with Lung Imaging to Generate Continuous Response Models
E. Parchuke Gow Effects of Chronic Pulmonary Inflammation on Ozone-Induced Alterations in the Lung Microbiome
J. Radbel D. Laskin Exacerbation of Sepsis-Induced Acute Lung Injury (ALI) by Ozone is Regulated by Macrophage Phenotypic Switching
T. Seymore D. Laskin Anti-TNFa Antibody Mitigates Sulfur Mustard-Induced Lung Injury in Rats
L.C. Smith D. Laskin Role of PPARγ in the Resolution of Ozone-Induced Lung Injury
A. Venosa Venosa Lung Epithelial Cell Susceptibility Driven by Surfactant Protein-C Mutation Enhances Ozone-Induced Toxicity
M. Wilkinson Gow OANO2 Increases the Likelihood of Survival and Resolution Signaling in Response to Bleomycin-Mediated Lung Injury
S. Xu Panettieri Free Fatty Acids Receptor 1/4 (FFAR1/4) Agonists, GW9508, and TAK875 Attenuate Agonist-Induced Shortening in Human Airway Smooth Muscle (HASM) Cells