The Graduate Research Fellowship in Toxicology from Bristol-Myers Squibb Co. supports students involved in non-clinical and in vivo toxicology research. Sixth year Ph.D. candidate Jessica Rodriguez was chosen as the 2026-2027 recipient of this competitive fellowship. Her research builds on the current understanding of the mechanisms of ozone-induced pulmonary injury and recovery, focusing on the integrated stress response (ISR) as a potential key pathway. The ISR is known to regulate inflammation and oxidative stress, two major consequences of inhaled ozone, but has not yet been studied in this context. The goal of this study is to evaluate the role of the ISR during ozone-induced lung injury and function as well as assess macrophage and neutrophil cellular responses in a mouse model deficient in ISR signaling. As climate change advances, exposure to ground-level ozone increases, demanding a better understanding of protective mechanisms against this insult. The Fellowship will support Jessica’s research costs, stipend, and allow for personalized mentoring from expert scientists at Bristol-Myers Squibb.