RATS Reunite at the Toxicology Gordon Conference

Current and former JGPT students, postdocs and faculty attended the 2019 Cellular and Molecular Mechanisms of Toxicity Gordon Conference in Andover, NH. The Chair of the conference, Dr. John Richburg, was a JGPT alumni and currently serves as Associate Dean for Research and Graduate Studies at the University of Texas at Austin. .

RATS Toxicity Challenge at Rutgers Day

 On Saturday April 27, 2019, the RATS embarked upon Cook Campus to welcome the NJ community to Rutgers as part of Rutgers Day. People were able to take selfies next to our famous RATS picture as well as play a game matching toxicants with target organs. Everyone learned a bit about physiology and toxicology while […]

Rutgers JGPT Hosts 2019 CounterACT Meeting

In June 2019, JGPT faculty Drs. Jeff Laskin, Laurie Joseph, Don Gerecke, and Debra Laskin hosted the annual meeting of the CounterACT program. Government, academic, and industry scientists from across the country attended the 3-day conference at the New York Academy of Sciences. Trainees Alexa Murray and Dr. Cody Smith were selected for podium presentations […]

Brushing Up on Biostatistics: Improving Toxicology Study Design and Evaluation

On May 23rd, the JGPT hosted a 3-hour bootcamp on biostatistics for current toxicology students as well as trainees and research scientists from across campus. Dr. Amy Kohtz provided case studies and a host of tools for the 25 participants to analyze their biological data. As students advance in their thesis projects and scientists prepare […]

Annual Celebration of RATS Research Accomplishments

On April 17, 2019, the Ernest Mario School of Pharmacy held its 9th annual Pharmacy Research Day. Students in the Joint Graduate Program in Toxicology presented their latest research findings ranging from oncology to liver disease to reproductive toxicology. The 2-hour dynamic event featured 114posters.  

Rutgers Scientists and Trainees Share Latest Research at SOT 2019 ToxExpo

In March 2019, the Rutgers Toxicology trainees attended the Society of Toxicology meeting in Baltimore, MD. Trainees (undergrad, grad and postdoc) presented over 35 posters and presentations throughout the week. During the meeting, Ludwik Gorczyca (Aleksunes lab) received the Sheldon Murphy Award (Mechanisms Specialty Section) and a 3rd Place Poster Award (Reproductive & Developmental Toxicology […]

2019 Society of Toxicology meeting in Baltimore, MD

 Infertility affects over 6 million women in the child bearing age with one main cause being women with progesterone resistance have a non-receptive uterus leading to implantation failure. To understand the mechanism behind this we looked at the role of Gαq/11 signaling since it’s been shown to regulate uterine functions throughout pregnancy from the acquisition of […]

2019 Society of Toxicology meeting in Baltimore, MD

  My research aims to define the effects of a small molecule, metabotropic glutamate receptor (mGluR) Group I agonist 2-chloro-5-hydroxyphenylglycine (CHPG), in a cuprizone-induced model of demyelination in mice. Demyelinating diseases such as Multiple Sclerosis can be very debilitating to patients and most of the current approved therapies treat the immunological component rather than the […]

2019 Society of Toxicology meeting in Baltimore, MD

  Syncytiotrophoblasts arise from the fusion of cytotrophoblasts, a process regulated by cyclic nucleotide signaling. Syncytiotrophoblasts express transporters, including the multidrug resistance-associated proteins (MRP) 1, 3, and 5, which regulate the intracellular concentration of cyclic nucleotides through active efflux. Understanding the interplay of cyclic nucleotides, efflux transporters, and syncytialization is important because aberrant cytotrophoblast functioning […]

2019 Society of Toxicology meeting in Baltimore, MD

My project focuses on the effects of vesicating agents, specifically nitrogen mustard (NM) on mouse skin. In these studies the epidermis is isolated and analyzed for protein changes involved in the cell cycle. A bi-phasic response was observed in proteins responsible for DNA synthesis and repair as early at 15 minutes following exposure up until 24 hours. This tells […]