Cody Smith was recently awarded a F32 NIH NRSA fellowship from NIEHS

Cody Smith was recently awarded a F32 NIH NRSA fellowship from the National Institute of Environmental Health Sciences to support his postdoctoral research investigating the role of macrophage subpopulations in chemical-induced lung injury and repair. Specifically, he will be investigating the role of PPARγ, a ligand-dependent transcription factor, in regulating anti-inflammatory macrophage phenotype and promoting […]

Raj Shah honored for excellent melanoma research

Raj Shah, PhD Candidate, was recently selected as a recipient of the Pan-American Society for Pigment Cell & Melanoma Research (PASPCR) Travel Award. Raj is scheduled to give a podium presentation titled “Concurrent targeting of glutaminolysis and metabotropic glutamate receptor 1 (GRM1) reduces glutamate bioavailability in GRM1+ melanoma” during the 2019 PASPCR Annual Meeting at […]

Brittany Karas recognized for outstanding zebrafish research

Over the past few months, Ph.D. candidate Brittany Karas has received a number of notable research awards. At the Gordon Research Seminar and Hudson-Delaware SETAC meetings this summer, Brittany received 1st Place for her research posters. Additional awards bestowed on Brittany in 2019 include the HDSETAC Student Travel Award, Douglas E. Eveleigh Travel Award, and […]

“Rutgers Pharmaceutical Research Travel Award”

  Raj Shah, a 5th year PhD Candidate, was recently selected as a recipient of the 2018-2019 Rutgers Pharmaceutical Research Travel Award, a program that has been generously made by Dr. Paul Kurtulik, an EMSOP alumni. Raj attended the 2019 Annual Meeting of the American Association for Cancer Research (AACR) in Atlanta, Georgia. Raj’s research […]

2019 Society of Toxicology meeting in Baltimore, MD

 Infertility affects over 6 million women in the child bearing age with one main cause being women with progesterone resistance have a non-receptive uterus leading to implantation failure. To understand the mechanism behind this we looked at the role of Gαq/11 signaling since it’s been shown to regulate uterine functions throughout pregnancy from the acquisition of […]

2019 Society of Toxicology meeting in Baltimore, MD

  Syncytiotrophoblasts arise from the fusion of cytotrophoblasts, a process regulated by cyclic nucleotide signaling. Syncytiotrophoblasts express transporters, including the multidrug resistance-associated proteins (MRP) 1, 3, and 5, which regulate the intracellular concentration of cyclic nucleotides through active efflux. Understanding the interplay of cyclic nucleotides, efflux transporters, and syncytialization is important because aberrant cytotrophoblast functioning […]

2019 Society of Toxicology meeting in Baltimore, MD

My project is on the role of Farnesoid X Receptor (FXR) in the lung following exposure to the chemical warfare agent, nitrogen mustard. FXR is a nuclear receptor involved in lipid homeostasis and we speculate that FXR regulates differential macrophage activation by altering lung lipids

2019 Society of Toxicology meeting in Baltimore, MD

Bile acids are a diverse population of amphipathic molecules synthesized through the enzymatic oxidation of cholesterol in the liver.  The synthesis of bile acids has traditionally been shown to occur via two pathways.  Cholesterol 7 alpha-hydroxylase (Cyp7a1) performs the initial and rate-limiting step in the classical pathway while sterol 27-hydroxylase (Cyp27a1) initiates the hydroxylation of […]

Training in PK Modeling as part of the SOT STEP Award Program

by Dahea “Diana” You This fall, I was fortunate to receive a generous funding from the Society of Toxicology Supplemental Training for Education Program (STEP) to attend a one-week comprehensive Simcyp® Workshop. This workshop was hosted by Certara and held at the Nassau Inn, Princeton NJ from October 22nd through 26th, 2018. The workshop program […]